Panther Fusion® GBS Assay
Accurate Group B Strep Screening using PCR NAAT: A Test You Can Trust
With performance you can trust, the Panther Fusion® GBS assay transforms your laboratory workflow and expands the molecular menu on the Panther Fusion® system. The assay detects the gram-positive bacterium Streptococcus agalactiae (GBS) from antepartum women, which demonstrated 100% sensitivity.1
Identify more true positive GBS mothers with a highly sensitive NAAT
ACOG and ASM guidelines suggest that all pregnant women be screened for GBS. Research indicates that screening with NAATs is highly sensitive and offers improved workflow and faster results compared to culture. Studies have shown that the Panther Fusion® GBS assay detects 31% more positives than culture, with less than 1 minute of hands-on time.2,3,4
Video Resources
The Panther Fusion GBS assay design1
Detects Group B Streptococcus DNA from antepartum women, following an 18–24-hour incubation in selective enrichment broth culture of Lim Broth or Carrot Broth.
Features dual-target detection of the Cfb and SIP genes, showing 100% clinical sensitivity and 96.5% specificity in a clinical trial.
Assay Specifications
Screening window:
Antepartum women
Specimen type:
Single vaginal-rectal swab3
Media Type:
Liquid Stuart’s or Amies
Enrichment broth:
Lim Broth or Carrot Broth
Turnaround time (TAT):
Quick TAT, <2.4 hours5
Saving Lives Through Accurate Detection: An Overview of GBS Screening Guidelines During Pregnancy
Panther Fusion® GBS Assay: Testing the Benefits of NAATs versus Culture for Group B Strep Screening
How much time and money could you save?
The Panther Fusion GBS assay run on the Panther Fusion system offers:
- Full automation
- High throughput
- Ready-to-use reagents with 30-60 day on board stability, eliminating reagent prep and waste1
- A non-batch workflow
Consolidate your group B strep testing on the Panther Fusion system with other Aptima® and Panther Fusion® assays for women’s health, virology, respiratory and sexually transmitted infections.
1. Panther Fusion GBS assay. US package insert AW-23714-001. Hologic, Inc.; 2022. 2. Shin JH and Pride DT. Comparison of Three Nucleic Acid Amplification Tests (NAATs) and Culture for Detection of Group B Streptococcus (GBS) from Enrichment Broth. J Clin Microbiology JCM.01958-18; DOI: 10.1128/JCM.01958-18 3. American Society for Microbiology. Guidelines for the Detection and Identification of Group B Streptococcus. ASM.org website. Last reviewed July 23, 2021. Accessed April 27,2023. https://asm.org/ASM/media/Protocol-Images/ASM-GBS-guideline.pd 4. Berry GJ, et al. Comparison of the Panther Fusion and BD MAX GBS Assays for Detection of Group B Streptococcus in Prenatal Screening Specimens. J Clin Microbiol. 2019; JCM.01034-19. 5. Data on file
